About Ion Beam Applications

Ion Beam Applications SA engages in the design and development of particle accelerators, therapeutic, and diagnostic dosimetry, and the production and distribution of radioisotopes. The company has designed cyclotrons and produces pharmaceutical tracers for the rapid, detection of, among others, cancer, and Alzheimer's and cardiovascular diseases. The company focuses on solutions, including proton therapy, high-energy electron treatment, brachytherapy, and dosimetry; they are all targeted at more accurate treatment and, the protection of healthy tissues. IBA customers include medical device manufacturers, cancer treatment centers, food processors, and the United States Postal Service. BUSINESS SEGMENTS The company operates in two segments: Radioisotopes Production & Distribution and Technology Services & Equipment RADIOISOTOPES PRODUCTION & DISTRIBUTION The company’s radioisotopes production & distribution segment engages in the production and distribution of radioisotopes for medical imaging and use in cancer treatment implants (brachytherapy). The company’s radiopharmaceutical products are used in medical imaging to aid in the diagnosis of cancer, and the production of implants used in the treatment of certain localized cancers, such as prostate and breast. Businesses within Radioisotope Production & Distribution include: FDG, Radiopharmaceuticals (nuclear medicine); and RadioMed (brachytherapy). The company’s brachytherapy business, RadioMed Corporation, is a fully owned subsidiary of IBA based in Tyngsboro, Massachusetts. RadioMed develops a brachytherapy implant based on a coiled-wire technology. The wire product, Radiocoil, offers advantages over the more traditional rice-size seeds, including improved dose distribution, stability of the implant, ultrasound visibility that enables precise placement, and a less invasive, less traumatic delivery procedure. Utilizing the coiled-wire technology, RadioMed has also introduced VISICOIL, an advanced linear, fiducial, soft tissue marker product. VISICOIL is designed to enhance the targeting capability of treatment techniques such as Proton Therapy and Intensity Modulated Radiation Therapy (IMRT), allowing increased dose to cancerous tissue while minimizing dose to surrounding healthy tissue. The company’s radiotherapeutic and diagnostic dosimetry business, Scanditronix - Wellhöfer, supplies dosimetry solution in the radiation therapy market. Its specialized dosimetry products measure the radiation dose to be administered to cancer patients during diagnosis and subsequent treatment with radiotherapy equipment. TECHNOLOGY SERVICES & EQUIPMENT The company’s technology services & equipment segment engages in the development, manufacture, and sale of proton and electron accelerators for applications in medicine and industry, as well as high-precision dosimetry tools and equipment for use within the radiation therapy market. The company offers its particle accelerator systems and dose verification equipment to hospitals, cancer treatment centers, Universities, research centers, device manufacturers and others within the healthcare market. Businesses within Technology Services & Equipment are: Scanditronix Wellhofer (dosimetry); IBA Proton Therapy (proton therapy); and IBA Technology group (cyclotrons / electron beam accelerators). Cyclotrons The company manufactures particle accelerators for the production of radioisotopes in the PET (positron emission tomography) and SPECT (single photo emission computer tomography) industries. SPECT cyclotrons: the Cyclone 30 is used mainly for the production of radioisotopes for diagnostic imaging in SPECT. PET cyclotrons: the Cyclone 18/9, Cyclone 10/5 and Cyclone 3 are dedicated to PET radioisotope productions. The company offers the cyclotron the infrastructure (building, vault and shielding) customized beam lines, lab equipment, radio-processing equipment, radioprotection systems, training, maintenance and upgrades. Electron Beam / X-Ray Accelerators The company produces high-power electron beam accelerators. The IBA system designs range in power up to 700 kW and provide for dual modality processing (electron beam and X-ray radiation), making its systems ideal for various products – medical devices, food, materials used in the production of everyday consumer products. Magnets & Coils-Scanditronix Magnet Scanditronix develops and manufactures complete magnets or coils alone. It can offer all types of magnets used in accelerator systems, such as bending magnets and quadrupoles, as well as other types of magnets. Significant Events On September 21, 2009, Ion Beam Applications SA and Aposense Ltd. announced an exclusive collaboration agreement for commercializing Aposense [18F]-ML-10, Aposense's agent for molecular imaging of apoptosis. [18F]-ML-10 is a small molecule radiotracer, which allows the imaging of apoptosis, a fundamental biological process of controlled cell death, from the early stages of the death process. As of September 15,2021 Ion Beam Applications S.A, and SCK CEN (Belgian Nuclear Research Center) announce a strategic R&D partnership to enable the production of Actinimum-225 (225Ac), a novel radioisotope which has significant potential in the treatment of cancer. As of October 25, 2021, Ion Beam Applications SA announced that it has signed an agreement with the University of Pennsylvania (Penn) to advance research in ConformalFLASH, a novel method combining ultra-high dose rate FLASH radiotherapy and the unique Bragg Peak properties of protons. History Ion Beam Applications SA was founded in 1986 by Yves Jongen.